Cyst of the Eyelid

Eyelid cysts are common benign lumps that form when oil glands in the eyelid become blocked, leading to swelling that can affect appearance, comfort, and sometimes vision.

Medical Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment.

Overview

Eyelid cysts are benign (non-cancerous) lumps that develop on or within the eyelids. The most common type is a chalazion, which forms when one of the meibomian glands—small oil-producing glands that line the eyelid margin—becomes blocked. These glands normally secrete oils that help lubricate the eye and prevent tear evaporation. When blocked, the oil backs up and forms a firm, round lump that can grow to the size of a small pea. Unlike styes, which are acute infections of eyelid glands, chalazia are typically painless and develop more gradually.

Eyelid cysts can occur on either the upper or lower eyelid and may affect one or both eyes. While they are generally harmless and often resolve on their own, larger cysts can cause cosmetic concerns, discomfort, and even interfere with vision if they grow large enough to press on the eyeball or distort the eyelid's shape. The condition affects people of all ages but is more common in adults aged 30-50 years. Individuals with certain skin conditions, such as rosacea or seborrheic dermatitis, are at higher risk of developing recurrent eyelid cysts.

Understanding eyelid cysts is important because while most are benign chalazia, other types of eyelid lumps can occur, including sebaceous cysts, inclusion cysts, and rarely, more serious conditions. Proper diagnosis ensures appropriate treatment and helps rule out other conditions that may require different management approaches. Most eyelid cysts can be effectively managed with conservative home treatments, though some may require medical intervention if they persist, recur frequently, or cause significant symptoms.

Symptoms

Eyelid cysts typically develop gradually and present with various symptoms depending on their size, location, and whether any secondary inflammation or infection is present.

Primary Symptoms

  • Mass on eyelid - A visible lump that may be firm, round, and moveable under the skin
  • Skin growth - Appears as a raised area on the eyelid that may increase in size over days to weeks
  • Muscle swelling - Swelling of the eyelid tissue surrounding the cyst
  • Abnormal movement of eyelid - Large cysts may cause the eyelid to droop or not close properly
  • Diminished vision - Large cysts pressing on the eyeball can cause blurred vision or astigmatism

Appearance Characteristics

  • Round or oval-shaped lump
  • Usually painless (unlike styes)
  • Firm to touch
  • May be skin-colored or slightly red
  • Can occur on upper or lower eyelid
  • Size ranges from small (few millimeters) to large (up to 8mm)

Associated Symptoms

  • Eyelid heaviness or feeling of pressure
  • Mild tenderness, especially when first developing
  • Increased tearing or watery eyes
  • Light sensitivity if cyst is large
  • Difficulty wearing contact lenses
  • Cosmetic concerns due to visible swelling

Symptoms by Cyst Type

Chalazion

  • Gradual onset over days to weeks
  • Initially may be slightly tender
  • Becomes painless firm lump
  • May have mild redness
  • Can persist for weeks to months

Infected Cyst (Secondary Infection)

  • Increased pain and tenderness
  • Red, warm, swollen eyelid
  • Possible discharge
  • May develop into preseptal cellulitis

Multiple or Recurrent Cysts

  • Several lumps on one or both eyelids
  • May indicate underlying skin condition
  • Chronic eyelid inflammation (blepharitis)
  • Recurring despite treatment

Impact on Daily Activities

  • Difficulty applying eye makeup
  • Self-consciousness about appearance
  • Discomfort when blinking
  • Problems with peripheral vision if large
  • Eye fatigue from compensating for vision changes

Causes

Eyelid cysts develop when glands or follicles in the eyelid become blocked, leading to accumulation of secretions. Understanding the underlying causes helps in prevention and treatment.

Primary Causes of Chalazion

Meibomian Gland Dysfunction

  • Blockage of oil-producing glands in eyelid
  • Thickened meibomian secretions
  • Inflammation of gland openings
  • Abnormal gland anatomy
  • Bacterial colonization of glands

Contributing Factors

  • Poor eyelid hygiene: Accumulation of debris and bacteria
  • Makeup residue: Blocking gland openings
  • Contact lens wear: Increased bacterial load
  • Rubbing eyes: Introducing bacteria and irritation
  • Environmental irritants: Dust, pollen, smoke

Underlying Conditions

Skin Conditions

  • Rosacea: Ocular rosacea affects eyelids
  • Seborrheic dermatitis: Oily, flaky skin
  • Acne: Similar pathophysiology
  • Eczema: Chronic skin inflammation
  • Psoriasis: May affect eyelid skin

Eyelid Conditions

  • Chronic blepharitis: Ongoing eyelid inflammation
  • Demodex mites: Follicle infestation
  • Trichiasis: Misdirected eyelashes
  • Entropion/Ectropion: Eyelid malposition

Other Types of Eyelid Cysts

Sebaceous Cysts

  • Blocked sebaceous glands
  • Filled with keratin material
  • Can occur anywhere on eyelid
  • Often have visible pore or punctum

Milia

  • Tiny white cysts
  • Trapped keratin under skin
  • Common in newborns
  • Usually multiple small bumps

Inclusion Cysts

  • Result from trauma or surgery
  • Epithelial cells trapped under skin
  • Slow-growing
  • Well-defined borders

Sweat Gland Cysts

  • Hidrocystoma
  • Clear fluid-filled cysts
  • Often on eyelid margin
  • May fluctuate in size

Systemic Factors

  • Hormonal changes: Pregnancy, menstruation
  • Stress: May affect oil gland function
  • Diet: High-fat diet may alter sebum composition
  • Medications: Some drugs affect gland secretions
  • Immunosuppression: Increased susceptibility

Environmental Triggers

  • Hot, humid climates
  • Air pollution
  • Occupational exposures
  • Poor air quality
  • Seasonal allergies

Risk Factors

Several factors increase the likelihood of developing eyelid cysts. Understanding these can help in prevention and early management.

Demographic Factors

  • Age: More common in adults 30-50 years
  • Gender: Slightly more common in women
  • Ethnicity: Higher prevalence in those with oily skin
  • Geographic location: Hot, humid climates

Medical Conditions

  • Chronic blepharitis: Major risk factor
  • Rosacea: Especially ocular rosacea
  • Seborrheic dermatitis: Oily skin condition
  • Diabetes: Increased infection risk
  • Inflammatory bowel disease: Associated skin manifestations
  • Acne history: Similar gland dysfunction

Lifestyle Factors

  • Poor eyelid hygiene: Not cleaning eyelids regularly
  • Makeup use: Especially if not removed properly
  • Contact lens wear: Increased bacterial exposure
  • Touching/rubbing eyes: Introduces bacteria
  • Sharing eye makeup: Cross-contamination
  • Using expired cosmetics: Bacterial growth

Previous History

  • Prior chalazion or stye
  • Recurrent eyelid infections
  • Previous eyelid surgery
  • History of acne
  • Family history of chalazia

Environmental Factors

  • Occupational dust or chemical exposure
  • Living in polluted areas
  • Exposure to smoke
  • Dry or windy conditions
  • Air conditioning exposure

Other Risk Factors

  • Stress: May affect immune function
  • Poor nutrition: Vitamin A deficiency
  • Dehydration: Affects gland secretions
  • Certain medications: Isotretinoin, hormone therapy
  • Immunosuppression: HIV, chemotherapy

Diagnosis

Diagnosis of eyelid cysts is primarily clinical, based on appearance and examination. However, distinguishing between different types of eyelid lumps is important for appropriate treatment.

Clinical Examination

Visual Inspection

  • Location: Upper or lower eyelid, margin or deeper
  • Size: Measured in millimeters
  • Shape: Round, oval, or irregular
  • Color: Skin-colored, red, or yellow
  • Surface: Smooth or irregular
  • Number: Single or multiple lesions

Palpation

  • Consistency: Firm, rubbery, or fluctuant
  • Mobility: Fixed or moveable
  • Tenderness: Painless or tender
  • Temperature: Normal or warm
  • Transillumination: For fluid-filled cysts

Detailed Eye Examination

  • Slit lamp examination: Detailed view of eyelid structures
  • Eversion of eyelid: Check inner surface
  • Meibomian gland assessment: Expression and quality of secretions
  • Tear film evaluation: Associated dry eye
  • Vision testing: If cyst affects sight

Differential Diagnosis

Benign Conditions

  • Stye (hordeolum): Acute, painful, infected gland
  • Milia: Multiple tiny white cysts
  • Xanthelasma: Yellow cholesterol deposits
  • Syringoma: Sweat gland tumors
  • Papilloma: Benign skin growth
  • Molluscum contagiosum: Viral infection

Concerning Conditions

  • Basal cell carcinoma: Most common eyelid cancer
  • Squamous cell carcinoma: Less common cancer
  • Sebaceous gland carcinoma: Can mimic chalazion
  • Melanoma: Rare but serious
  • Lymphoma: Very rare

When Further Testing is Needed

Indications for Biopsy

  • Recurrent cyst in same location
  • Atypical appearance
  • Failed response to treatment
  • Rapid growth
  • Ulceration or bleeding
  • Loss of eyelashes
  • Patient over 40 with new growth

Imaging Studies

  • Ultrasound: For deep or large cysts
  • CT or MRI: If orbital extension suspected
  • Photography: Document size and appearance

Laboratory Tests

Usually not needed, but may include:

  • Culture if secondary infection
  • Histopathology after excision
  • Lipid profile if multiple xanthelasma
  • Blood glucose if recurrent infections

Red Flags Requiring Urgent Referral

  • Rapid growth over weeks
  • Ulceration or bleeding
  • Loss of eyelashes around lesion
  • Distortion of eyelid architecture
  • Multiple recurrences in same spot
  • Associated vision changes

Treatment Options

Treatment of eyelid cysts depends on the size, symptoms, and duration. Many chalazia resolve spontaneously, but various interventions can speed recovery and provide relief.

Conservative Management

Warm Compresses

  • Method: Clean washcloth with warm water
  • Temperature: Comfortably warm, not hot
  • Duration: 10-15 minutes
  • Frequency: 4-6 times daily
  • Technique: Gentle pressure and massage
  • Purpose: Softens blocked secretions

Eyelid Massage

  • After warm compress application
  • Gentle circular motions
  • Direction: Toward eyelid margin
  • Duration: 2-3 minutes
  • Clean hands essential

Eyelid Hygiene

  • Baby shampoo: Diluted for daily cleaning
  • Commercial lid scrubs: Pre-moistened pads
  • Tea tree oil products: For demodex
  • Hypochlorous acid spray: Antimicrobial
  • Technique: Gentle scrubbing of lid margins

Medical Treatments

Topical Medications

  • Antibiotic ointments:
    • Erythromycin ophthalmic
    • Bacitracin
    • Tobramycin
  • Combination drops: Antibiotic-steroid
  • Application: To eyelid margin 2-4 times daily

Oral Medications

  • Antibiotics for chronic cases:
    • Doxycycline: Anti-inflammatory properties
    • Azithromycin: Pulse therapy
    • Duration: 4-6 weeks or longer
  • Omega-3 supplements: Improve oil gland function

Steroid Injections

  • Intralesional triamcinolone
  • For persistent chalazia
  • Small volume (0.1-0.2 mL)
  • May require repeat injection
  • Risk of skin depigmentation

Surgical Interventions

Incision and Curettage

  • Indications:
    • Failed conservative treatment (4-6 weeks)
    • Large cysts affecting vision
    • Cosmetic concerns
    • Recurrent cysts
  • Procedure:
    • Local anesthesia
    • Incision from conjunctival side
    • Curettage of contents
    • No external scar

External Excision

  • For cysts pointing externally
  • Suspicious lesions requiring biopsy
  • Careful technique to avoid scarring
  • Send tissue for pathology

Alternative Treatments

  • Intense Pulsed Light (IPL): For associated rosacea
  • LipiFlow: Thermal pulsation for gland dysfunction
  • Meibomian gland probing: Opens blocked glands
  • BlephEx: Mechanical lid margin cleaning

Post-Treatment Care

  • Continue warm compresses
  • Antibiotic ointment as prescribed
  • Avoid eye makeup for 1 week
  • No contact lenses for 24-48 hours
  • Follow-up as directed

Managing Recurrent Cysts

  • Identify underlying conditions
  • Long-term oral antibiotics
  • Regular lid hygiene routine
  • Dietary modifications
  • Stress management
  • Consider biopsy for repeated same-site recurrence

Expected Timeline

  • Conservative treatment: 2-8 weeks for resolution
  • Post-injection: 1-2 weeks improvement
  • Post-surgery: 1-2 weeks healing
  • Complete resolution: May take 1-3 months

Prevention

Preventing eyelid cysts focuses on maintaining good eyelid hygiene and managing underlying conditions that increase risk.

Daily Eyelid Hygiene

  • Regular cleaning: Daily eyelid hygiene routine
  • Remove makeup: Thoroughly every night
  • Clean applicators: Don't share makeup tools
  • Replace cosmetics: Follow expiration dates
  • Avoid touching: Keep hands away from eyes

Lifestyle Modifications

  • Diet:
    • Increase omega-3 fatty acids
    • Reduce inflammatory foods
    • Stay hydrated
    • Limit dairy if sensitive
  • Stress management: Regular relaxation practices
  • Adequate sleep: 7-8 hours nightly
  • Exercise: Improves circulation

Managing Risk Factors

  • Treat underlying blepharitis
  • Control rosacea with medications
  • Manage seborrheic dermatitis
  • Regular eye exams
  • Control diabetes if present

Environmental Precautions

  • Use humidifier in dry environments
  • Wear wraparound sunglasses outdoors
  • Avoid smoke and irritants
  • Clean air filters regularly
  • Protect eyes from wind and dust

Contact Lens Care

  • Proper hygiene before handling
  • Replace lenses as scheduled
  • Clean cases regularly
  • Use fresh solution daily
  • Consider daily disposables

Makeup and Cosmetic Tips

  • Choose non-comedogenic products
  • Avoid waterproof formulas
  • Clean brushes weekly
  • Don't use testers on eyes
  • Remove before exercise

For High-Risk Individuals

  • Prophylactic warm compresses
  • Regular meibomian gland expression
  • Maintenance oral antibiotics if needed
  • Quarterly eye care visits
  • Early intervention at first signs

When to See a Doctor

While many eyelid cysts resolve with home treatment, certain situations require professional medical evaluation.

Seek Immediate Care For

  • Sudden vision changes or loss
  • Severe eye pain
  • Signs of spreading infection (fever, facial swelling)
  • Double vision
  • Inability to move eye normally
  • Rapidly growing mass

Schedule an Appointment For

  • Cyst persisting more than 2-3 weeks
  • Recurrent cysts in same location
  • Multiple cysts developing
  • Cyst affecting vision
  • Significant cosmetic concerns
  • Associated eyelash loss
  • Bleeding or ulceration

Consider Specialist Referral For

  • Failed conservative treatment
  • Atypical appearance
  • Need for surgical intervention
  • Underlying skin conditions
  • Chronic eyelid inflammation
  • Suspicious features

Follow-Up Care

  • Post-surgical check at 1 week
  • Monitor for recurrence
  • Annual eye exams if prone to cysts
  • Earlier if new symptoms develop

References

  1. Gilchrist H, Lee G. Management of chalazia in general practice. Aust Fam Physician. 2009;38(5):311-314.
  2. Arbabi EM, Kelly RJ, Carrim ZI. Chalazion. BMJ. 2010;341:c4044.
  3. Nemet AY, Vinker S, Kaiserman I. Associated morbidity of chalazia. Cornea. 2011;30(12):1376-1381.
  4. Wu AY, Gervasio KA, Gergoudis KN, et al. Conservative therapy for chalazia: is it really effective? Acta Ophthalmol. 2018;96(5):e503-e509.
  5. Lindsley K, Nichols JJ, Dickersin K. Interventions for acute internal hordeolum. Cochrane Database Syst Rev. 2017;1:CD007742.
  6. Goawalla A, Lee V. A prospective randomized treatment study comparing three treatment options for chalazia: triamcinolone acetonide injections, incision and curettage and treatment with hot compresses. Clin Exp Ophthalmol. 2007;35(8):706-712.
  7. Mustafa TA, Oriafage IH. Three methods of treatment of chalazia in children. Saudi Med J. 2001;22(11):968-972.
  8. Garrett GR, Gillespie ME. Evaluation and management of the patient with chalazion. J Am Optom Assoc. 1987;58(3):224-226.
  9. Jordan GA, Beier K. Chalazion. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021.
  10. American Academy of Ophthalmology. Chalazion and Stye Treatment. EyeNet Magazine. 2020.

Frequently Asked Questions

Is a chalazion the same as a stye?

No, they're different conditions. A stye is an acute infection of an eyelid gland that's painful and develops quickly. A chalazion is a chronic inflammatory lump that develops slowly and is usually painless. Styes can sometimes develop into chalazia if not properly treated.

Can I pop an eyelid cyst?

No, you should never attempt to pop or squeeze an eyelid cyst. This can spread infection, cause scarring, and potentially damage your eye. Warm compresses and massage are safe ways to encourage drainage, or see an eye doctor for professional treatment.

How long does a chalazion last?

With conservative treatment (warm compresses and lid hygiene), most chalazia resolve within 2-8 weeks. Some may persist for months if untreated. Larger cysts or those not responding to home treatment may require medical intervention.

Are eyelid cysts contagious?

No, chalazia and most eyelid cysts are not contagious. They result from blocked glands, not infections that can spread. However, if secondary bacterial infection occurs, proper hygiene is important to prevent spreading bacteria to the other eye.

Can eyelid cysts come back?

Yes, chalazia can recur, especially in people with underlying conditions like blepharitis, rosacea, or seborrheic dermatitis. Good eyelid hygiene and treating underlying conditions can reduce recurrence risk. Repeated cysts in the same location should be evaluated by a doctor.

When is surgery necessary?

Surgery (incision and drainage) is considered when a chalazion doesn't respond to 4-6 weeks of conservative treatment, affects vision, causes significant cosmetic concerns, or recurs frequently. The procedure is minor and performed under local anesthesia.